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1.
J Obstet Gynaecol India ; : 1, 2023 Apr 29.
Article in English | MEDLINE | ID: covidwho-2323914

ABSTRACT

[This corrects the article DOI: 10.1007/s13224-022-01737-5.].

2.
J Obstet Gynaecol India ; : 1, 2023 Apr 29.
Article in English | MEDLINE | ID: covidwho-2315800

ABSTRACT

[This corrects the article DOI: 10.1007/s13224-022-01737-5.].

3.
J Obstet Gynaecol India ; 73(3): 279-281, 2023 Jun.
Article in English | MEDLINE | ID: covidwho-2175214

ABSTRACT

Postpartum collapse is a life-threatening condition caused by obstetrical and non-obstetrical events. In this case report, we discuss a case of postpartum collapse in COVID-19-positive woman who required intensive care and mechanical ventilation for two days. After confusing collision of many provisional diagnoses soldiering for three days, she was ultimately diagnosed with malignant catatonia. Targeted therapy with lorazepam challenge resulted in drastic improvement, and she was discharged with her baby in healthy condition.

4.
Placenta ; 127: 1-7, 2022 09.
Article in English | MEDLINE | ID: covidwho-1937084

ABSTRACT

INTRODUCTION: This study aims at observing placental pathologies in COVID-19 infected women, and analyzing its impact on pregnancy outcome. METHOD: This is a descriptive-analytical study done at a tertiary centre of Northern India. All COVID-19 positive pregnant women with gestational age ≥20 weeks, with placental histopathological reporting, were included in this study. A total of 173 COVID-19 pregnant women were included in the study. RESULTS: Placental abnormalities were noticed in 49·16% of total 179 placentae examined. Maternal vascular malperfusion (27·93%) was the most observed placental pathology followed by villous fibrin deposits (22·90%), fetal vasculopathy (16·75%), and acute inflammation (6·70%). Stillbirths were 22 and NICU admissions were seen in 50 neonates. Abnormal placental abnormalities led to higher stillbirths (p value 0·011) and lower Apgar scores at 1 and 5 min (p-value 0·028; p-value 0·002, respectively). Intervillous fibrin deposits had higher risk associated with lower Apgar score at 1 and 5 min [RR 2·05 (95% CI 1·21-3·48, p-value 0·010) and RR 5·52 (95% CI 2·58-11·81, p-value <0·001), respectively]. RP clot/hemorrhage was also associated with lower Apgar score at 1 and 5 min [RR 2·61 (95% CI 1·52-4·49, p-value 0·002) and RR 3.54 (95% CI 1·66-7·55, p-value 0·001), respectively]. DISCUSSION: Placental abnormalities in COVID-19 infection were associated with significant higher incidence of unexplained stillbirths, and lower Apgar scores. Although, this is the largest descriptive-analytical study done so far, comparative studies are required to draw a clear conclusion regarding the impact of COVID-19 infection on human placenta and its effect on pregnancy outcomes.


Subject(s)
COVID-19 , Placenta Diseases , Pregnancy Complications, Infectious , Female , Fibrin , Humans , Infant , Infant, Newborn , Mothers , Placenta/pathology , Placenta Diseases/pathology , Pregnancy , Pregnancy Outcome , Stillbirth/epidemiology
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